Mast Cell in the Skin: Inflammation Culprit?

Mast cells(MCs) are best known for being essential effector cells in allergic reactions of the acute variety, which can even result in potentially fatal toxic shock syndromes. Yet, MCs also contribute significantly to the first line of defence against pathogens due to their strategic positioning at the host-environment interfaces and abundance of receptors.

 

In addition to being harmful to diseases caused by MCs, MCs also exacerbate other inflammatory skin disorders.

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